Microvascular changes in shock

  1. Homepage
  2. Why this site?
  3. References for this site
  4. Stage 1: Pre-shock Anticipation
  5. Stage 2: Pre-shock Slide
  6. Stage 3: Compensated shock
  7. Stage 4: Decompensated shock, but reversible
  8. Stage 5: Decompensated shock, but irreversible
  9. Vicious cycles
  10. S.I.R.S.
  11. Shock Combo
  12. Microvascular Complications
  13. Geneva Handshake
  14. EGDT
  15. Normotensive and Hypertensive (cryptic) Shocks
  16. contact

In severe shock the microcirculation changes dramatically. Those changes are mainly due to a "cytokine storm" induced by extremely severe tissue ischemia or, directly, by a pathogen: (1) the endothelium is activated (vasodilates, becomes pro-coagulant, expresses adhesion molecules), (2) monocytes are activated (and discharge numerous cytokines), (3) white blood cells obstruct some capillaries (4) disseminated intra-vascular coagulation and platelet aggregation plug microcirculation as well.
When there is so much deterioration to the microcirculation, perfusion to organs worsens rapidly....and, as a consequence, systemic shock also worsens extremely rapidly... we are very close to the end, Folks...! ...(cute diagram but bad for the patient...)



This Dancing Empire asked the rolex replica limited time scale report feature excellence at the same time full of replica rolex strong artistic atmosphere, peacock feathers, mysteriously enveloped the sexy dancer. Peacock's feathers unfold to reveal the dancers' gestures through the activity doll's questionnaire function. Glamorous charming ballroom dancer on the hairpin on a red flower, sexy high-heeled sandals, with a replica watches uk charming gesture and charm eyes to tease the immediate audience, blow shells breakable carcass, hidden in replica watches the colorful peacock feathers .